EARTH – Cohort of Early Anti-Retroviral Treatment in HIV-perinatally infected Children is a prospective multicentre, low-interventional study of HIV+ perinatally infected children on sustained suppressive antiretroviral therapy (ART) commenced before 3 months of age.
The primary objective is to describe the natural history of early treated children (<3 months) in order to identify children with an HIV excellent control at age 3 in limited-resource settings.
150 children have been enrolled in 5 sites in South Africa and Mozambique.
The EARTH study is sponsored by Fondazione Penta Onlus.
