Born from the collaboration among EPPICC and EPIICAL, the paper “Predictors of faster virological suppression in early treated infants with perinatal HIV from Europe and Thailand” demonstrates that even amongst HIV infected infants initiating combination antiretroviral therapy (cART) within 6 months of life, earlier treatment initiation predicts faster virological suppression. Higher baseline CD4 in percentage and lower HIV viral load are also independent predictors of faster virological suppression. Strongly, these results provide additional support for earlier cART initiation in infants with perinatal HIV and indicate that early treatment influences key virological and immunological parameters that could have important consequences for long term health.
The full text version will be soon available in the section Publications.