The CARMA (Child and Adolescent Reservoir Measurements on early suppressive ART) GLOBAL cohort includes 96 children perinatally-infected, adolescents and youth who are early-treated and have been on ART for 7 or more years and who are currently suppressed.
This study aims to investigate viral reservoir functionality and immunogenic correlations, with the ultimate goal of identifying a substantial minority (8-25%) who will have a low and undetectable viral reservoir with limited functionality, making them ideal candidates for subsequent studies of new interventions.
What have we achieved?
The study protocol has been submitted to the various local regulatory bodies for approval.
Countries involved:
